MUC2, MUC4 and MUC5AC expression in carcinoma gallbladder
نویسندگان
چکیده
منابع مشابه
Prognostic significance of muc4 expression in gallbladder carcinoma
BACKGROUND Mucins are high molecular glycoproteins and play protective and lubricating roles in various epithelial tissues. Deregulated expression of mucins is involved in carcinogenesis and tumor invasion. MUC4 expression has been identified as a poor prognostic factor in pancreatobiliary carcinomas. To date, the relation between MUC4 expression and prognosis in gallbladder carcinoma remains t...
متن کاملExpression of MUC1 and MUC4 in Gallbladder Adenocarcinoma
BACKGROUND Recent reports have indicated that overexpression of mucin (MUC) 1 and/or MUC4 correlates with the occurrence and progression of extra-hepatobiliary malignancy. In this study, we investigated the expression of MUC1 and MUC4 and their prognostic significance in gallbladder adenocarcinoma. METHODS We examined 54 surgical gallbladder adenocarcinoma samples by immunohistochemistry for ...
متن کاملExpression in Gallbladder Carcinoma
Cytokeratin expression is being frequently used for the differential diagnosis of carcinomas originating from different sites. Among the various cytokeratins, the combination of cytokeratins (CKs) 7 and 20 is considered to be the most useful for this purpose. However, there are very few reports in the literature regarding CK7 and CK20 expression in gallbladder carcinoma (GBC). In this paper we ...
متن کاملPrognostic significance of MUC1, MUC2 and MUC5AC expressions in gastric carcinoma.
BACKGROUND/AIMS The aim of this study was to investigate the expressions of some of the Mucus Core Proteins (MUC) MUC1, MUC2 and MUC5AC in gastric carcinomas, to assess their prognostic values and their relations with the clinicopathological characteristics. METHODS MUC1, MUC2 and MUC5AC expressions were investigated immunohistochemically in 257 patients with gastric carcinomas. RESULTS MUC...
متن کاملQuantification of MUC2 and MUC5AC transcripts in human conjunctiva.
PURPOSE Transcripts of mucins 1, 4, and 5AC have been identified in human conjunctival tissue. Of these, only MUC5AC has been localized to goblet cells. MUC2 is a goblet cell mucin originally identified in the intestinal mucosa. The presence of MUC2 transcripts and levels of MUC2 and MUC5AC transcripts in normal human conjunctiva, as determined by quantitative polymerase chain reaction (PCR), i...
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ژورنال
عنوان ژورنال: HPB
سال: 2018
ISSN: 1365-182X
DOI: 10.1016/j.hpb.2018.06.094